Leprosy—History, Ætiology, Bacteriology and Pathology

De-Novo Presentation of Histoid Leprosy on an Unusual Site

Histoid Leprosy (HL) is a rare variant of Lepromatous Leprosy, occurring in long-standing cases, mostly in a background of acquired drug resistance. Patients usually present with sudden onset multiple nodules and plaques, most often involving the skin and subcutaneous tissue of trunk and lower limbs. Here we report an unusual case of de novo (without any history of prior anti-leprotic therapy) ...

A Textbook of Bacteriology: The Application of Bacteriology and Immunology to the Ætiology, Diagnosis. Specific Therapy and Prevention of Infectious Diseases for Students and Practitioners of Medicine and Public Health

Leprosy in children: correlation of clinical, histopathological, bacteriological and immunological parameters.

The study of leprosy in children has indicated an incidence of 10% amongst leprosy patients attending the clinic. The duration of the disease was usually less than 2 years. The expression of leprosy in this group was either a macule and/or a plaque. Classification was, therefore, different and conforms to indeterminate (I), borderline tuberculoid (BT) and borderline (BB) leprosy. Only occasiona...

A Study of the Clinico-Bacteriology and Antibiotic Sensitivity Profile of Plantar Ulcers in Leprosy

Introduction: Leprosy is a chronic granulomatous disease with widespread involvement of the body including peripheral nerves. Chronic ulcers are among the most dreaded complications of leprosy with high bacterial load resulting in delayed wound healing.The ulcers are recurrent, which increase the physical disability and mortality due to leprosy. The secondary bacterial infection in the plantar ...

Langerhans Cells in Skin Lesions of Leprosy

Background: Langerhans cells are important in the pathogenesis of leprosy.  A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...